Mehlisch 1990.
Methods | RCT, DB, single oral dose, 3 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 30, 60 mins, then hourly up to 6 hours. |
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Participants | Various oral surgery procedures N = 705 (697 analysed for efficacy) M = 277, F = 420 Mean age 31 years |
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Interventions | Ibuprofen 400 mg, n = 306 Paracetamol 1000 mg, n = 306 Placebo, n = 85 |
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Outcomes | PI: std 4 point scale PR: non‐std 4 point scale Numbers of participants using rescue medication Numbers with any adverse event Withdrawals |
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Notes | Oxford Quality Score: R1, DB1, W1 Rescue medication permitted (time not specified). |