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. 2009 Jul 8;2009(3):CD001548. doi: 10.1002/14651858.CD001548.pub2

Mehlisch 1990.

Methods RCT, DB, single oral dose, 3 parallel groups
Medication administered when baseline pain was of moderate to severe intensity
Pain assessed at 0, 30, 60 mins, then hourly up to 6 hours.
Participants Various oral surgery procedures
N = 705 (697 analysed for efficacy)
M = 277, F = 420
Mean age 31 years
Interventions Ibuprofen 400 mg, n = 306
Paracetamol 1000 mg, n = 306
Placebo, n = 85
Outcomes PI: std 4 point scale
PR: non‐std 4 point scale
Numbers of participants using rescue medication
Numbers with any adverse event
Withdrawals
Notes Oxford Quality Score: R1, DB1, W1
Rescue medication permitted (time not specified).