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. 2009 Jul 8;2009(3):CD001548. doi: 10.1002/14651858.CD001548.pub2

Nørholt 1998.

Methods RCT, DB, single oral dose, 2 parallel groups
Medication administered when baseline pain was of moderate to severe intensity
Pain assessed at baseline, then hourly up to 4 hours.
Participants Third molar extraction
N = 57
M = 21, F = 36
Mean age 24 years
Interventions Ibuprofen 400 mg, n = 26
Placebo, n = 31
Outcomes PI: non‐std 5 point scale
PR: 5 point scale ‐ reverse wording
Numbers of participants using rescue medication
Withdrawals
Notes Oxford Quality Score: R1, DB2, W1
Rescue medication (paracetamol) permitted.