Olson 2001.
Methods | RCT, DB, single oral dose, 4 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 15, 30, 45, 60, 90, 120 mins, then hourly up to 6 hours. |
|
Participants | Third molar extraction N = 239 M = 76, F = 163 Mean age 23 years |
|
Interventions | Ibuprofen liquigel 400 mg, n = 67 Ketoprofen 25 mg, n = 67 Paracetamol 1000 mg, n = 66 Placebo, n = 39 |
|
Outcomes | PI: std 4 point scale PR: std 5 point scale PGE: std 5 point scale Numbers of participants using rescue medication Time to use of rescue medication Numbers with any adverse event Withdrawals |
|
Notes | Oxford Quality Score: R2, DB2, W1 Rescue medication (standard analgesic) permitted. |