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. 2009 Jul 8;2009(3):CD001548. doi: 10.1002/14651858.CD001548.pub2

Olson 2001.

Methods RCT, DB, single oral dose, 4 parallel groups
Medication administered when baseline pain was of moderate to severe intensity
Pain assessed at 0, 15, 30, 45, 60, 90, 120 mins, then hourly up to 6 hours.
Participants Third molar extraction
N = 239
M = 76, F = 163
Mean age 23 years
Interventions Ibuprofen liquigel 400 mg, n = 67
Ketoprofen 25 mg, n = 67
Paracetamol 1000 mg, n = 66
Placebo, n = 39
Outcomes PI: std 4 point scale
PR: std 5 point scale
PGE: std 5 point scale
Numbers of participants using rescue medication
Time to use of rescue medication
Numbers with any adverse event
Withdrawals
Notes Oxford Quality Score: R2, DB2, W1
Rescue medication (standard analgesic) permitted.