Sunshine 1996.
Methods | RCT, DB, single oral dose, 6 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 30, 60 mins, then hourly up to 6 hours. |
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Participants | Episiotomy N = 305 All F Mean age 23 years |
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Interventions | Ibuprofen 50 mg, n = 51 Ibuprofen 100 mg, n = 51 Ibuprofen 200 mg, n = 50 Ibuprofen 100 mg + caffeine 100 mg, n = 50 Ibuprofen 200 mg + caffeine 100 mg, n = 50 Placebo, n = 50 |
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Outcomes | PI: std 4 point scale PR: std 5 point scale PGE: non‐std 4 point scale Numbers of participants using rescue medication Numbers with any adverse event Withdrawals |
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Notes | Oxford Quality Score: R1, DB2, W1 Rescue medication permitted after 1 hour. |