Wideman 1999 (study 1).
Methods | RCT, DB, single oral dose, 4 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 20, 40, 60, 80, 100, 120, 150, 180 mins, then hourly up to 7 hours. |
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Participants | Abdominal or gynaecological surgery N = 240 All F Mean age 39 years |
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Interventions | Ibuprofen 200 mg, n = 60 Ibuprofen 200 mg, + hydrocodone 7.5 mg, n = 59 Hydrocodone 7.5 mg, n = 61 Placebo, n = 60 |
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Outcomes | PI: std 4 point scale PR: std 5 point scale PGE: std 5 point scale Numbers with any adverse event Withdrawals |
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Notes | Oxford Quality Score: R1, DB2, W1 Rescue medication permitted after 1 hour. |