Wideman 1999 (study 2).

Methods	RCT, DB, single oral dose, 4 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 20, 40, 60, 80, 100, 120, 150, 180 mins, then hourly up to 8 hours.
Participants	Abdominal or gynaecological surgery N = 201 All F Mean age 40 years
Interventions	Ibuprofen 400 mg, n = 50 Ibuprofen 400 mg + hydrocodone 15 mg, n = 50 Hydrocodone 15 mg, n = 50 Placebo, n = 51
Outcomes	PI: std 4 point scale PR: std 5 point scale PGE: std 5 point scale Numbers of participants using rescue medication Time to use of rescue medication Numbers with any adverse event Withdrawals
Notes	Oxford Quality Score: R1, DB2, W1 Rescue medication permitted after 1 hour.