| Methods | Randomly assigned - method not described. | |
| Participants | Inclusion criteria: gestational age 9 to 13 weeks, viable embryo with an intact sac | |
| Interventions | Transcervical performed under direct ultrasound guidance. 16 G cannula passed via the cervix to chorion frondosum and villi aspirated with suction. Transabdominal CVS was performed using continuous ultrasound guidance and an 18 G needle passed to reach the border of the chorion frondosum. A 20 G needle was then passed through this first needle and villi aspirated | |
| Outcomes | Technical difficulty, fetal loss rate and speed of procedure | |
| Notes | ||
| Risk of bias | ||
| Item | Authors’ judgement | Description |
| Allocation concealment? | Unclear | B - Unclear |
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