Table 3.
Episodes, Incidence Densities, and Rate Ratios of Respiratory-Tract Infections, by Treatment Group
| CQ-AZ |
CQ |
Rate Ratio (95% CI) | P Value | |||
|---|---|---|---|---|---|---|
| Count | Rate | Count | Rate | |||
| All RTI events | 65 | 0.53 | 90 | 0.79 | 0.67 (.48, .94) | .02 |
| Lower RTI events | 47 | 0.39 | 65 | 0.57 | 0.67 (.45, .99) | .05 |
| Upper RTI events | 3 | 0.02 | 4 | 0.04 | 0.70 (.10, 4.13) | .92 |
| Otitis media events | 15 | 0.12 | 21 | 0.19 | 0.66 (.32, 1.35) | .29 |
Rate calculated as event per total person-years of follow-up (CQ-AZ = 121.7, CQ = 113.3). Total person-years calculated as total time from enrollment until censoring at termination from the study. Rate ratio is event rate for chloroquine-azithromycin over the rate for chloroquine monotherapy.
Abbreviations: CI, confidence interval; CQ: chloroquine monotherapy group; CQ-AZ, chloroquine-azithromycin group; RTI, respiratory-tract infection.