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FSD-C10 inhibits Rho kinase (ROCK) activity. Brain, spinal cord and spleen of mice with experimental autoimmune encephalomyelitis (EAE) treated with nasal FSD-C10 or saline were harvested at day 28 post-immunization (n = 12 each group). These tissues were homogenized, and ROCK activity in the supernatant fraction was measured by commercial kit. **P < 0·01.
