Figure 2.

FSD-C10 ameliorates the severity of experimental autoimmune encephalomyelitis (EAE) and improves demyelination. FSD-C10 was given by nasal instillation and saline was set up as control (n = 12 each group) in a similar manner. (a) Clinical score of EAE mice and mean bodyweight, and (b) representative microphotographs for demyelination (Luxol Fast Blue staining) and quantitative analysis of spinal cord lesions. Data represent mean standard error (SEM) of demyelination score from seven or eight mice in each group. *P < 0·05, **P < 0·01, ***P < 0·001.