Table 3.
Clinical data on fenofibrate products
| Product | Formulation | Clinical efficacy | Safety | Strength | Cost* |
|---|---|---|---|---|---|
| Antara® | Micronized capsule | No mortality benefit in those with type 2 diabetes.102–104 | No differences in safety outcomes | 30 mg 43 mg+ 90 mg 130 mg+ |
$78.42 $70.58 $230.88 $207.79 |
| Fenoglide | MeltDose tablets | 40 mg 120 mg |
$106.20 $318.96 |
||
| Lofibra® | Film-coated tablet (formerly Tricor®2) Micronized capsule (formerly Tricor®1) |
54 mg+ 160 mg+ 67 mg+ 134 mg+ 200 mg+ |
$23.76 $74.63 $31.70 $58.77 $94.52 |
||
| Lipofen® | Lidose capsule | 50 mg 150 mg |
$87.96 $191.44 |
||
| Tricor® | Nanocrystal (Tricor®NP) | Lipid profile shows decreased TG and LDL. Questionable clinical significance.105,106 Bioequivalence for Tricor®NP and Tricor®1.100 |
48 mg+ 145 mg+ |
$57.29 $171.86 |
|
| Triglide® | IDD-P | Equivalent absorption when compared to Tricor®1 and Tricor®2.107 | 160 mg | $239.70 |
Notes:
*
Cost relates to price per 30 days.
+
Generic available; priced according to generic price.
Abbreviations: IDD-P, Insoluble Drug Delivery – Particles™ technology; LDL, low-density lipoprotein cholesterol; TG, triglycerides.