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. 2014 Sep 22;211(10):2061–2074. doi: 10.1084/jem.20132494

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Figure 2. — Neutralization of two R5-tropic SHIVs with a panel of 11 broadly acting anti–HIV-1 mAbs. (A and C) Neutralization was performed with SHIV_AD8EO (A) or SHIV_DH12-V3AD8 (C) pseudovirions and the indicated mAbs using TZM-bl target cells. The titration curves for the glycan-dependent neutralizing mAbs are red; for VRC01 in blue; and two potent CD4bs mAbs (45-46m2 and 3BNC117) in green. (B and D) The calculated IC₅₀ values for neutralizing SHIV_AD8EO (B) or SHIV_DH12-V3AD8 (D) are shown below. The individual assays were repeated three times.

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