Table 2.
Plasma neutralizing antibody concentrations and titers at the time of virus challenge
| Animal ID | Abs | Dosage | PROTECTED | Ab concentration at day 0 | Titer (TZM-bl) at day 0 |
| mg/kg | µg/ml | ||||
| SHIVAD8EO Challenged Animals | |||||
| DEGF | VRC01 | 50 | Yes | 586.9 | 1:162 |
| DEH3 | No | 711.0 | 1:176 | ||
| DE1L | 20 | No | 206.5 | 1:65 | |
| JBN | No | 188.1 | 1:80 | ||
| KNX | PGT121 | 20 | Yes | 267.9 | 1:2,495 |
| MK4 | Yes | 253.6 | 1:2,773 | ||
| DE9J | 5 | Yes | 55.7 | 1:563 | |
| PNR | No | 47.2 | 1:618 | ||
| DCGI | 1 | Yes | 24.0 | 1:116 | |
| KNE | Yes | 19.7 | 1:55 | ||
| K44 | 0.2 | No | 1.8 | <1:20 | |
| K49 | No | 1.8 | 1:17 | ||
| DEEM | 10-1074 | 20 | Yes | 289.8 | 1:2,004 |
| KIL | Yes | 257.7 | 1:2,075 | ||
| ME1 | 5 | Yes | 112.9 | 1:633 | |
| PNV | Yes | 117.5 | 1:384 | ||
| PID | 1 | No | 19.9 | 1:56 | |
| DCHX | No | 24.8 | 1:53 | ||
| PZE | 3BNC117 | 5 | Yes | 105.4 | 1:272 |
| PM5 | Yes | 76.1 | 1:372 | ||
| KMH | 1 | No | 39.6 | 1:55 | |
| MJ5 | No | 15.1 | 1:75 | ||
| PLD | 45-46m2 | 20 | No | 15.0 | 1:27 |
| MA9 | No | 17.6 | <1:20 | ||
| MC6 | 5 | No | 2.3 | <1:20 | |
| DE0CA | No | 2.2 | <1:20 | ||
| ML1 | DEN3 | 20 | No | ND | <1:20 |
| MAA | No | ND | <1:20 | ||
| SHIVDH12-V3AD8 Challenged Animals | |||||
| DEJ3 | VRC01 | 30 | Yes | 395.8 | 1:52 |
| KZ1 | No | 306.0 | 1:70 | ||
| KZA | PGT121 | 20 | Yes | 215.1 | 1: 13,120 |
| DECT | Yes | 200.7 | 1: 13,805 | ||
| KTL | Yes | 282.7 | 1: 12,669 | ||
| PZ9 | Yes | 133.1 | 1: 12,055 | ||
| K2Z | 1 | Yes | 15.1 | 1:422 | |
| MT8 | No | 29.3 | 1:539 | ||
| DEEB | 0.2 | Yes | 3.1 | 1:159 | |
| DEP2 | Yes | 1.6 | 1:101 | ||
| MFD | 0.05 | No | 1.0 | <1:20 | |
| KIA | No | 1.3 | <1:20 | ||
| KIM | 10-1074 | 20 | Yes | 290.3 | 1:1,972 |
| KWM | Yes | 173.3 | 1:2,282 | ||
| MJW | 5 | Yes | 96.6 | 1:420 | |
| MJT | Yes | 95.3 | 1:376 | ||
| DENI | 1 | Yes | 28.4 | 1:106 | |
| JHZ | No | 18.6 | 1:136 | ||
| HE8 | 0.2 | No | 19.4 | 1:39 | |
| KCZ | No | 19.7 | 1:35 | ||
| MFBA | 3BNC117 | 20 | Yes | 294.9 | 1:143 |
| MER | Yes | 272.7 | 1:142 | ||
| KIV | 5 | Yes | 114.6 | 1:80 | |
| KPI | No | 133.1 | 1:90 | ||
| DE9D | 1 | No | 23.3 | 1:20 | |
| DEW7 | Yes | 29.6 | 1:18 | ||
| MEV | 0.2 | No | 3.9 | <1:20 | |
| MF9 | No | 5.7 | <1:20 | ||
| KZMA | 45-46m2 | 5 | No | 2.1 | ND |
| KNP | No | 4.0 | ND | ||
| JII | hu-IgG | 100 | No | ND | ND |
| JK1 | No | ND | ND | ||
ND, not done.