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. 2014 Sep 22;211(10):1977–1991. doi: 10.1084/jem.20132620

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© 2014 Rowland et al.

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Figure 9. — Reduced lupus-associated soluble factors and inflammatory chemokines in sera after early pDC depletion. Male DTR⁺ and DTR^– mice were treated with DT and analyzed at 11 or 19 wk of age, as marked. Age-matched, untreated, healthy female littermates are included. Concentration of soluble (A) VCAM-1, (B) CD40L, (C) MPO, and (D) select chemokines in sera of indicated mice were determined by serum protein array. Data points indicate samples from individual mice analyzed by MyriadRBM rodent MAPv3.0 array. *, P < 0.5; **, P < 0.01; ***, P < 0.001. Absence of * indicates nonsignificant differences.