Bone marrow eosinophil and neutrophils (%) for individual subjects (ATP population). Only subjects who consented to bone marrow aspiration and provided evaluable samples at screening and endpoint are included.
a) Eosinophils. Cohort 1 IV: placebo n = 1, square with dashed line; benralizumab 1 mg/kg n = 4, diamond with solid line. Cohort 2 SC: benralizumab 100 mg n = 1, circle with solid line.
b) Neutrophils and bands. Cohort 1 IV: placebo, n = 1; benralizumab 1 mg/kg, n = 4. Cohort 2 SC: benralizumab 100 mg n = 1.