Table 3.

Mean change in non-motor measures from OFF induced by worse-side, right and left brain subthalamic nucleus (STN DBS).

Outcome Measure and DBS Side	Number of Participants with improved scores	Number of Participants	Mean difference from OFF DBS	Standard deviation	t statistic	p- value
Cognition
SDR (error in mm)
Worse	20	39	0.09	0.30	1.93	0.061
Right	19	44	0.08	0.38	1.37	0.180
Left	17	39	0.01	0.23	0.30	0.764
Go/No-Go (Pr)
Worse	11	23	−0.04	0.26	−0.74	0.47
Right	13	27	−0.01	0.17	−0.43	0.67
Left	13	22	−0.11	0.29	−1.83	0.08
Psychiatric
Valence
Worse	18	23	0.24	0.35	3.33	0.003
Right	16	24	0.13	0.34	1.86	0.076
Left	18	22	0.27	0.36	3.54	0.002
Arousal
Worse	9	23	0.01	0.39	0.11	0.910
Right	13	24	−0.04	0.21	−0.87	0.400
Left	8	23	0.00	0.40	−0.003	1.000
Anxiety
Worse	19	25	−10.57	25.58	−2.07	0.050
Right	19	26	−6.41	21.52	−1.52	0.140
Left	16	23	−13.20	25.05	−2.53	0.020
Apathy a
Worse	16	25	11.64	29.59	1.97	0.060
Right	15	27	0.26	25.57	0.05	0.958
Left	14	24	12.38	35.25	1.72	0.100
Akathisia b
Worse	14	25	−4.20	27.08	−0.78	0.446
Right	16	27	1.37	18.26	0.39	0.700
Left	13	24	−5.96	28.08	−1.04	0.309

SDR, spatial delayed response task; mm, millimeter; Pr, ability to discriminate between ‘Go’ and ‘No-Go’ stimuli.

^aPositive mean difference score for apathy indicates decreased apathy/increased motivation.

^bNegative mean difference score for akithisia indicates decreased restlessness.