Table 1. Bias (precision) of parameters estimated using the liquid- or air-filled catheters compared to those obtained with the balloon catheter, in different conditions.
balloon Vs. | EL | Ecw | ΔPtrans | Ptrans,endexp | PTP | WOBi | |||||||||||
[cmH2O/L] | [cmH2O/L] | [cmH2O] | [cmH2O] | [cmH2O•s] | [cmH2O•L] | ||||||||||||
spont BIPAP | 7.9 | (8.2) | ** | −1.3 | (1.5) | ** | −0.3 | (2.2) | 0.8 | (0.6) | *** | 0.3 | (0.3) | ||||
contr BIPAP | −2.7 | (5.3) | 1.8 | (5.3) | −1.0 | (2.4) | 0.1 | (2.2) | |||||||||
contr MV | −2.0 | (5.0) | ** | 2.0 | (5.0) | ** | −0.6 | (1.4) | ** | −1.1 | (1.4) | *** | |||||
spont BIPAP | 7.7 | (7.6) | ** | 0.3 | (0.9) | −0.9 | (2.4) | 0.4 | (1.0) | 0.2 | (0.5) | ||||||
contr BIPAP | 0.8 | (7.4) | −1.6 | (7.0) | −0.5 | (3.0) | −0.9 | (2.5) | |||||||||
contr MV | 2.4 | (5.5) | ** | −2.4 | (5.5) | ** | 0.6 | (1.6) | * | −1.2 | (2.0) | *** |
BIPAP: biphasic positive airway pressure; contr MV: controlled mechanical ventilation (with animal paralyzed using atracurium bromide); contr BIPAP: assisted ventilation (allowing unsupported spontaneous breaths), considering only the controlled breaths; spont BIPAP: assisted ventilation, considering only the unsupported spontaneous breaths. EL, Ecw: lung and chest wall elastance; ΔPtrans: inspiratory change in transpulmonary pressure; Ptrans,end-exp: end-expiratory value of transpulmonary pressure; PTP: pressure-time product; WOBi: inspiratory work of breathing. Significance of t-test:
*p<0.05;
**p<0.01;
***p<0.001.