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. 2014 Sep 23;9(9):e103057. doi: 10.1371/journal.pone.0103057

Table 1. Bias (precision) of parameters estimated using the liquid- or air-filled catheters compared to those obtained with the balloon catheter, in different conditions.

balloon Vs. EL Ecw ΔPtrans Ptrans,endexp PTP WOBi
[cmH2O/L] [cmH2O/L] [cmH2O] [cmH2O] [cmH2O•s] [cmH2O•L]
spont BIPAP 7.9 (8.2) ** −1.3 (1.5) ** −0.3 (2.2) 0.8 (0.6) *** 0.3 (0.3)
contr BIPAP −2.7 (5.3) 1.8 (5.3) −1.0 (2.4) 0.1 (2.2)
contr MV −2.0 (5.0) ** 2.0 (5.0) ** −0.6 (1.4) ** −1.1 (1.4) ***
spont BIPAP 7.7 (7.6) ** 0.3 (0.9) −0.9 (2.4) 0.4 (1.0) 0.2 (0.5)
contr BIPAP 0.8 (7.4) −1.6 (7.0) −0.5 (3.0) −0.9 (2.5)
contr MV 2.4 (5.5) ** −2.4 (5.5) ** 0.6 (1.6) * −1.2 (2.0) ***

BIPAP: biphasic positive airway pressure; contr MV: controlled mechanical ventilation (with animal paralyzed using atracurium bromide); contr BIPAP: assisted ventilation (allowing unsupported spontaneous breaths), considering only the controlled breaths; spont BIPAP: assisted ventilation, considering only the unsupported spontaneous breaths. EL, Ecw: lung and chest wall elastance; ΔPtrans: inspiratory change in transpulmonary pressure; Ptrans,end-exp: end-expiratory value of transpulmonary pressure; PTP: pressure-time product; WOBi: inspiratory work of breathing. Significance of t-test:

*p<0.05;

**p<0.01;

***p<0.001.