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. 2014 Sep 23;9(9):e107318. doi: 10.1371/journal.pone.0107318

Figure 2. Targeted Analysis of Differentially Methylated Loci in Preeclampsia.

Figure 2

Locus-specific analysis of CpG methylation in normal controls and preeclampsia samples was carried out by Sequenom Epityper (TLE1, IRAK1) (n = 24 controls and n = 24 PE samples) or high-throughput bisufite sequencing (n = 12 controls and n = 12 PE). Samples from pregnancies involving female (left panel) and male (right panel) fetuses were analyzed separately. Statistically significant differences in% methylation between samples are marked with **. Genomic coordinates corresponding to values on the x-axis can be found in Table S6A in File S1.