Table 3. Fetal Gender-Dependent Preeclampsia-Associated Changes in Placental DNA Methylation.

Illumina Probe Identifier	% meth PE	% meth Norm	Combined pvalue	Combined Adj. pvalue	Chr	Symbol	Distance to TSS	CPG Island
cg23717696	77	57	2.9E-05	0.05	X	ITGB1BP2	432	FALSE
cg09528351	54	40	1.9E-04	0.05	17	PIK3R5	432	FALSE
cg07864297	40	26	1.3E-04	0.05	14	ESRRB	157	FALSE
cg05275605	59	47	1.1E-03	0.09	21	C21orf123	102	TRUE
cg07017706	58	46	5.8E-04	0.08	12	K6IRS3	988	FALSE
cg14358743	65	54	1.2E-03	0.09	13	GAS6	1223	TRUE
cg14886269	41	30	1.0E-03	0.09	1	TNFRSF18	162	TRUE
cg01560871	62	51	5.6E-04	0.08	10	C10orf27	267	FALSE
cg17229388	66	55	1.4E-04	0.05	13	MGC35169	128	TRUE
cg16698623	71	61	6.4E-04	0.08	10	MGMT	NA	TRUE
cg01910481	74	63	7.1E-05	0.05	20	PLUNC	266	FALSE

CpG sites at which samples from affected individuals (PE) are more highly methylated (10% or greater) than those from normal controls (Norm) are shown. Significant adjusted p values (FDR controlled at 10%) were only identified in pregnancies in which the fetal gender was female.