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. Author manuscript; available in PMC: 2014 Sep 23.
Published in final edited form as: Exp Neurol. 2011 Dec 8;233(2):783–790. doi: 10.1016/j.expneurol.2011.11.042

Fig. 7.

Fig. 7

VPA enhanced H3 acetylating and BDNF transcript in spinal neurons. (A) Neurons were immunostained with antibodies to β-III tubulin (red) and acetylated histone 3 (green). Compared to controls, VPA (1.2 mM) increased Ac-H3. (B) Weston blot was performed to quantify Ac-H3. VPA significantly enhanced H3 acetylating in neurons attained from spinal cord. (C) The level of BDNF mRNA in spinal cord neurons was measured by q-PCR. Compared to controls, VPA significantly upregulated BDNF transcript. Data were presented as means±SEM (n=3), Bar=100 μm, p<0.05* and p<0.01**.