. 2014 Sep 23;11(9):e1001735. doi: 10.1371/journal.pmed.1001735

Table 3. Malaria-related outcomes at delivery.

Outcomes	Control		MQ		RR or Difference	95% CI	p-Value
	n/N	Percent	n/N	Percent
Maternal parasitemia (smear or PCR)
ITT [N = 973]	37/490	7.6	17/483	3.5	0.47^a	(0.27–0.82)	0.008
ATP [N = 859]	31/443	7.0	16/416	3.8	0.54^a	(0.30–0.97)	0.038
Placental infection (histology, smear, or PCR)
ITT [N = 911]	34/462	7.4	17/449	3.8	0.52^a	(0.29–0.90)	0.021
ATP [N = 808]	30/418	7.2	16/390	4.1	0.51^a	(0.30–0.89)	0.017
Maternal anemia (Hb<11 g/dl)
ITT [N = 963]	187/484	38.6	190/479	39.7	1.02^a	(0.88–1.19)	0.758
ATP [N = 849]	155/436	35.6	161/413	39.0	1.11^a	(0.94–1.31)	0.232
Severe maternal anemia (Hb<7 g/dl)
ITT [N = 963]	12/484	2.5	11/479	2.3	0.93^a	(0.41–2.08)	0.857
ATP [N = 849]	10/436	2.3	10/413	2.4	0.89^a	(0.35–2.27)	0.814
Maternal Hb, mean (SD) [n]
ITT [N = 963]	11.3 (2.2) [484]		11.2 (2.1) [479]		−0.03^b	(−0.28 to 0.22)	0.826
ATP [N = 849]	11.4 (2.2) [436]		11.3 (2.1) [413]		−0.09^b	(−0.35 to 0.18)	0.521
Low birth weight (<2,500 g)
ITT [N = 975]	46/486	9.5	61/489	12.5	1.32^a	(0.90–1.95)	0.157
ATP [N = 865]	35/441	7.9	48/424	11.3	1.39^a	(0.89–2.17)	0.147
Birth weight, mean (SD) [n]
ITT [N = 975]	3,059.3 (575.5) [486]		3,036.3 (570.6) [489]		−22.50^b	(−98.31 to 53.32)	0.561
ATP [N = 865]	3,100.4 (529.9) [441]		3,055.6 (540.4) [424]		−38.84^b	(−114.01 to 36.33)	0.312
Gestational age at birth (weeks), mean (SD) [n]^c
ITT [N = 436]	38.8 (1.1) [230]		38.7 (1.3) [236]		−0.10^b	(−0.32 to 0.13)	0.405
ATP [402]	38.9 (1.1) [205]		38.8 (1.2) [197]		−0.07^b	(−0.32 to 0.17	0.551
Cord blood parasitemia (smear)
ITT [N = 933]	3/462	0.6	1/471	0.2	0.33^a	(0.03–3.13)	0.334
ATP [N = 836]	3/424	0.7	1/412	0.2	0.24^a	(0.04–1.49)	0.126
Cord blood anemia (Hb<12.5 g/dl)
ITT [N = 930]	67/459	14.6	80/471	17.0	1.17^a	(0.87–1.58)	0.303
ATP [N = 835]	63/424	14.9	73/411	17.8	1.20^a	(0.88–1.64)	0.257
Maternal parasitemia one month post- delivery (smear)
ITT [N = 836]	7/423	1.7	8/413	1.9	1.20^a	(0.44–3.26)	0.721
ATP [N = 732]	6/377	1.6	8/355	2.3	1.45^a	(0.55–3.87)	0.454

RR.

Mean difference.

Assessed by the Ballard score (excluding incomplete data). ITT analysis adjusted by country. ATP analysis adjusted by baseline variables (country, literacy, gestational age, gravidity, anemia, middle upper arm circumference, and CD4).