Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Loss-of-function of thioredoxin reductase Trr1 results in constitutive oxidation of thioredoxins, which leads to suppression of mutation formation through two distinct mechanisms. Yap1 activation and consequent over-expression of Yap1-regulated oxido-reductases play a major role in reducing mutagenesis. TLS, translesion DNA synthesis.
