Table 4. In vitro a cytotoxicity of harmalol (IC50 b µM).
| Cancer cell lines | 72 hrs incubation with the alkaloid (in µM) |
| HeLac | 42 |
| MDA-MB-231c | 24 |
| A549c | 45 |
| HepG2c | 14 |
a
Data represent the mean values of three independent determinations.
b
Cytotoxicity as IC50 for cell line is the concentration of compound which reduced by 50% the optical density of treated cells with respect to untreated cells using MTT assay.
c
Cell lines include non small cell cervical carcinoma (Hela), breast carcinoma (MDA-MB-231), lung carcinoma (A549) and liver carcinoma (HepG2).