Table 3.
Hepatic cholesterol |
Biliary lipid secretion |
||||||
Unesterified | Ester | Bile flow | Cholesterol | Bile salts | Phospholipids | ||
Group | Liver weight | (mg/g liver weight) | (mg/g liver weight) | (μL/min/100 g body weight) | (nmol/min/100 g body weight) | (nmol/min/100 g body weight) | (nmol/min/100 g body weight) |
Ad.E1Δ | 1.32 ± 0.04 (n = 11) | 1.97 ± 0.08 | 0.20 ± 0.08 | 9.43 ± 0.76 (n = 8) | 2.75 ± 0.33 | 254.1 ± 34.2 | 84.25 ± 5.5 |
Ad.MLN64 | 1.14 ± 0.04 (n = 16)a | 2.38 ± 0.08a | 0.21 ± 0.07 | 4.14 ± 0.61a | 1.38 ± 0.19a | 308.5 ± 45.4 | 54.64 ± 13.5 |
Measurements were performed in six mice in each experimental group, except for liver weight and bile flow as indicated.
P < 0.05 vs Ad.E1Δ-infected mice.