Table 2.
Maternal dietary intake of folate and vitamin B12 and MTHFR genotypes
| Maternal characteristic | First trimester | Third trimester |
|---|---|---|
| (n = 231) | (n = 231) | |
| Nutrients dietary intake (%) | ||
| Energy (Kcal/d) | ||
| Mean ± SD | 2,822.84 ± 902.75 | 2,809.76 ± 892.65 |
| Folate (<400 μg/d) | 144 (62.34 %) | 147 (63.64 %) |
| B12 Vitamin (<2.0 μg/d) | 43 (18.61 %) | 44 (19.05 %) |
| Calcium (<1,200 mg/d) | 143 (61.90 %) | 130 (56.28 %) |
| Iron (<30 mg/d) | 208 (90.04 %) | 212 (91.77 %) |
| Zinc (<15 mg/d) | 220 (95.24 %) | 228 (98.70 %) |
| MTHFR genotypes (%) | ||
| MTHFR 677 C>T a | ||
| CC | 36 (15.58) | – |
| CT | 115 (49.78) | – |
| TT | 80 (34.63) | – |
| MTHFR 677 C>T | ||
| C | 187 (40.48) | – |
| T | 275 (59.52) | – |
| MTHFR 1298A>C b | ||
| AA | 187 (81.66) | – |
| AC | 38 (16.59) | – |
| CC | 4 (1.75) | – |
| MTHFR 1298 A>C | ||
| A | 412 (89.96) | |
| C | 46 (10.04) |
aHardy–Weinberg equilibrium test = 0.61
bHardy–Weinberg equilibrium test = 0.25