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. 2014 Sep 26;6(4):421–431. doi: 10.4252/wjsc.v6.i4.421

Figure 1.

Figure 1

B cell development in bone marrow. B lineage cells are differentiated from hematopoietic stem cells (HSC) through the several steps defined by the distinct surface phenotypes of positive (red) or negative (green) expression. The comparison between mouse (upper side) and human (lower side) is shown. MPP: Multipotent progenitors; LMPP/ELP: Lymphoid-primed multipotent/ early lymphoid progenitors; CLP: Common lymphoid progenitors; IL7Ra: IL-7 receptor alpha.