Table 3.
Cellular changes in HVC and the vVZ
| No. of days | LD+T 28 | SD |
ANOVA | |||||
|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 4 | 7 | 14 | 28 | |||
| HVC | (n = 6) | (n = 7) | (n = 8) | (n = 7) | (n = 7) | (n = 5) | (n = 6) | |
| AC-3 cell no. | 836 ± 142a | 1351 ± 309a,b | 1681 ± 222b | 1062 ± 68a,b | 865 ± 91a | 1313 ± 131a,b | 1081 ± 151a,b | F(6, 39)=2.8600, p = 0.0207 |
| (n = 9) | (n = 5) | (n = 7) | (n = 8) | (n = 7) | (n = 6) | (n = 7) | ||
| BrdU-positive neuron no. | 162 ± 30 | 103 ± 31 | 113 ± 29 | 120 ± 20 | 103 ± 17 | 61 ± 15 | 76 ± 11 | F(6,42)=2.0819, p = 0.0758 |
| vVZ | (n = 5) | (n = 5) | (n = 6) | (n = 9) | (n = 5) | (n = 6) | (n = 6) | |
| BrdU-positive cell no. | 631 ± 51a | 1116 ± 73a,b | 1680 ± 225a,b | 2246 ± 303b | 1018 ± 235a,b | 893 ± 185a,b | 1187 ± 149a,b | F(6,35)=6.6854, p < 0.0001 |
| Coefficient of determination | (n = 6) | (n = 5) | (n = 6) | (n = 8) | (n = 5) | (n = 5) | (n = 4) | |
| vVZ proliferation to HVC AC-3 no. |
R2 = 0.8696, p = 0.0208 |
R2 = 0.4469, p = 0.1466 |
R2 = 0.0028, p = 0.9212 |
R2 = 0.4009, p = 0.5544 |
R2 = 0.0352, p = 0.8124 |
R2 = 0.8641, p = 0.2404 |
R2 = 0.9067, p = 0.0479 |
|
All values are mean ± SEM.
a,bDenotes significant differences across treatment groups.