Figure 7.

DIMM-dependent transactivation of putative syta regulatory fragments. In vitro transactivation assay presents a systematic analysis of eight fragments derived from the syta genomic locus fused to luciferase. PHM is a fragment of the first intron of the Phm gene, which is an established DIMM target. Top, Map of the genomic fragments within the syta locus. Small black boxes represent positions of E-boxes (putative DIMM binding sites) that have the dinucleotide GC or TA in the middle two positions.