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. 2014 Sep 17;22(1):63. doi: 10.1186/s40199-014-0063-8

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© Azadmehr et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The effect of Z. tenuior L. extract on allogenic MLR. In order to find the effects of the Z. tenuior L. extract on allogenic immune response, DCs were treated with the extract for 18 h and then co-cultured with allogenic T cells for 48 h. DMSO-treated DCs plus T cells was considered as control. Brdu incorporation assay was used for measuring of cell proliferation. The results show mean ± SD of the cell proliferation in the presence of the extract as compared to the proliferation of controls taken to be 100%. Our results indicated that DCs treated with 100 μg/ml of extract significantly (*P < 0.05) have decreased T cells proliferation.