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. 2014 Sep 5;13:128. doi: 10.1186/s12933-014-0128-5

Table 2.

Relative risk of cardiovascular events

HR (95% CI) p value
baPWV (per 1 SD)
  Model 1 1.67 (1.44-1.93) <0.001
  Model 2 1.46 (1.23-1.73) <0.001
  Model 3 1.32 (1.09-1.59) 0.005
  Model 4 1.35 (1.11-1.64) 0.003
  Model 4 + maxIMT 1.33 (1.09-1.62) 0.004
maxIMT (per 1 SD)
  Model 1 1.46 (1.28-1.66) <0.001
  Model 2 1.29 (1.11-1.50) 0.001
  Model 3 1.22 (1.03-1.44) 0.019
  Model 4 1.22 (1.03-1.46) 0.022
  Model 4 + baPWV 1.21 (1.01-1.44) 0.036

Cox proportional hazards regression analyses unadjusted (Model 1) and adjusted for the following covariates:

Model 2, adjusted for gender and age.

Model 3, adjusted for gender and the other statistically significant variables in the unadjusted analyses (age, duration of diabetes, presence of hypertension at baseline, baseline systolic blood pressure, serum creatinine level, and Framingham risk score).

Model 4, adjusted for the conventional risk factors and baseline therapies (gender, age, smoking habit, BMI, HbA1c, duration of diabetes, systolic blood pressure, HDL cholesterol, LDL cholesterol, triglyceride, serum creatinine level, administration of anti-diabetic drugs, anti-hypertensive drugs, and anti-hyperlipidemic drugs).