Table 3.
Fracture risk among patients with osteoporosis during the 3-year follow-up period from index health care utilization
| Patients with dementia N = 349 | Comparison patients N = 1497 | |||
|---|---|---|---|---|
| Osteoporosis group | N | % | N. | % |
| Total | ||||
| Osteoporosis | 87 | 24.93 | 330 | 22.04 |
| Crude HR (95% CI) | 1.33 (1.04- 1.69)* | 1.00 | ||
| Adjusted HR (95% CI) | 1.32 (0.98- 1.78) | 1.00 | ||
| Hip fracture | ||||
| Osteoporosis | 25 | 7.16 | 64 | 4.28 |
| Crude HR (95% CI) | 1.98 (1.24- 3.15)* | 1.00 | ||
| Adjusted HR (95% CI) | 2.27 (1.28- 4.01)* | 1.00 | ||
| Wrist fracture | ||||
| Osteoporosis | 13 | 3.72 | 34 | 2.27 |
| Crude HR (95% CI) | 1.85 (0.92- 3.70) | 1.00 | ||
| Adjusted HR (95% CI) | 2.39 (0.98- 5.80) | 1.00 | ||
| Vertebral fracture | ||||
| Osteoporosis | 45 | 12.89 | 213 | 14.23 |
| Crude HR (95% CI) | 1.07 (0.78- 1.48) | 1.00 | ||
| Adjusted HR (95% CI) | 0.87 (0.58- 1.30) | 1.00 | ||
*P < 0.05. HR, hazard ratio; CI, confidence interval. Hazard ratios were calculated with the stratified Cox proportional regression method (stratified by sex, age group, and the year of index health care use) during the 3-year follow-up period. Adjustments were made for Charlson Comorbidity Index in the patients.