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Summary of anti-human Tetherin, CD4, NTB-A and CD155 activity of Vpu proteins derived from HIV-1 M NL4-3, SIVgsn 166, SIVcpz EK505, SIVgor CP2139 or HIV-1 N CK1.62 HIV-1 P RBF168 isolates (Bolduan et al., 2013; Sauter et al., 2011; Sauter et al., 2009).
| Vpu alleles | Tetherin | CD4 | NTB-A | CD155 |
|---|---|---|---|---|
| HIV-1 M NL4-3 | + | + | + | + |
| SIVgsn 166 | + | + | + | − |
| SIVcpz EK505 | − | + | + | − |
| SIVgor CP2139 | − | + | + | +/− |
| HIV-1 N CK1.62 | + | − | − | − |
| HIV-1 P RBF168 | − | + | n.d. | − |
