Table 3.

Clinical and pathological complete responses

	All patients		p53 wild type		p53 mutated
	FEC arm N=928	T-ET arm N=928	FEC arm N=427	T-ET arm N=398	FEC arm N=318	T-ET arm N=326
Complete clinical response (cCR)	121	155	51	65	55	56
cCR% (95% CI) *	13.0 (10.9–15.5)	16.7 (14.4–19.3)	11.9 (9.0–15.4)	16.3 (12.8–20.3)	17.3 (13.3–21.9)	17.2 (13.2–21.7)
Odds ratio (98% CI)*	1.34 (0.99–1.82)		1.44 (0.90–2.30)		0.99 (0.61–1.61)
p-value	0.031		0.072		1.00
Complete pathological response (pCR)	218	246	79	80	93	97
pCR% (95% CI) *	23.5 (20.8–26.4)	26.5 (23.7–29.5)	18.5 (14.9–22.5)	20.1 (16.3–24.4)	29.2 (24.3–34.6)	29.8 (24.8–35.0)
Odds ratio (98% CI)*	1.17 (0.92–1.51)		1.11 (0.73–1.67)		1.02 (0.69–1.53)
p-value	0.148		0.60		0.93

Abbreviations

cCR: complete clinical response

pCR: pathological complete response

^*95% confidence intervals of observed rates (by arm) and estimates, and 98% confidence intervals of odds ratio (between arms)