(b).
(n = 6) | Sodium (mmol/L) | Potassium (mmol/L) | Chloride (mmol/L) | Urea (mmol/L) | Creatinine (μmol/L) | |
---|---|---|---|---|---|---|
Control | Female | 148.6 ± 0.4 | 39.6 ± 1.6 | 106.4 ± 2.3 | 7.9 ± 0.1 | 31.8 ± 0.6 |
Male | 142.5 ± 1.5 | 54.8 ± 2.2 | 111.7 ± 2.1 | 7.2 ± 1.0 | 32 ± 2.9 | |
Vehicle | Female | 143.2 ± 1.2 | 39.8 ± 0.8 | 109.4 ± 1.6 | 7.2 ± 1.2 | 32.8 ± 1.1 |
Male | 145.2 ± 1.7 | 59.8 ± 2.02 | 115.7 ± 1.6 | 7.7 ± 1.1 | 33.2 ± 1.8 | |
ZER (100 mg/kg) | Female | 151.5 ± 0.5 | 41.7 ± 0.3 | 108.2 ± 0.7 | 8.4 ± 1.0 | 35.6 ± 0.8 |
Male | 144.7 ± 2.1 | 57.3 ± 1.9 | 112.1 ± 2.7 | 7.3 ± 2.3 | 35.8 ± 3.1 | |
ZER (200 mg/kg) | Female | 153.2 ± 0.3 | 44.4 ± 1.6 | 111.06 ± 2.1 | 8.8 ± 2.2 | 37.2 ± 3.2 |
Male | 145.8 ± 1.9 | 56.4 ± 3.3 | 117.05 ± 3.1 | 7.9 ± 3.5 | 35.6 ± 2.7 | |
NLC (100 mg/kg) | Female | 152 ± 0.9 | 43.7 ± 0.5 | 107.7 ± 0.6 | 7.35 ± 0.1 | 33.53 ± 0.8 |
Male | 142.6 ± 3.0 | 56.2 ± 3.3 | 107.8 ± 0.3 | 6.3 ± 1.7 | 31.3 ± 1.5 | |
NLC (200 mg/kg) | Female | 145.4 ± 0.6 | 43.2 ± 0.4 | 106.7 ± 0.6 | 6.4 ± 0.4 | 34.6 ± 1.5 |
Male | 141.1 ± 1.0 | 550.4 ± 1.4 | 108.5 ± 1.3 | 6.3 ± 1.1 | 36.7 ± 2.5 | |
ZER-NLC (100 mg/kg) | Female | 146.4 ± 0.8 | 44.5 ± 0.4 | 106 ± 0.2 | 6.6 ± 0.3 | 33.8 ± 0.1 |
Male | 140.2 ± 3.0 | 55.2 ± 2.5 | 107.4 ± 3.1 | 6.9 ± 0.4 | 34.6 ± 2.5 | |
ZER-NLC (200 mg/kg) | Female | 146.9 ± 0.7 | 47 ± 0.2 | 107.8 ± 0.3 | 6.5 ± 0.3 | 36 ± 0.2 |
Male | 141.9 ± 2.1 | 56.8 ± 3.8 | 112.3 ± 2.5 | 7.8 ± 1.2 | 29.7 ± 2.6 |
Treatment was performed for 14 days. Values are mean ± SD (n = 6) and have been analyzed using post hoc comparison test one way ANOVA. Data revealed nonsignificant (P > 0.05) difference in liver function test after 14 days in all treated groups when compared to that of untreated control group.