Figure 5. Quantitative mutant analysis and model fitting.

(a) Measured mRNA concentrations for all genes other than the stripe-forming gene at 6 h of growth. Mean and s.d. from three biological replicates. (b) Comparison of WT (green) and mutant (orange) network fluorescence at 6 h of growth. The interactions marked with an asterisk are modified in the mutant networks. The exact changes and conditions are listed in Supplementary Fig. 7. Mean and s.d. from three biological replicates. The black lines represent the model fitted simultaneously to the RNA data and fluorescence output of the WT and mutant networks for each design class.