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Dance of neutrophils. Leukocyte capture, rolling, adhesion, and transmigration through the endothelial cell barrier. PSGL, P selectin glycoprotein ligand; LSG, L selectin glycoprotein ligand; ICAM, intercellular adhesion molecule. Initial capture of leukocytes is mediated via selectin (endothelial P/E selectin binds PSGL); tight adhesion is mediated via integrins (neutrophil beta-2, leukocyte function associated antigen, CD11/CD18 binds ICAM).
