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. 2014 Jun 19;30(19):2779–2786. doi: 10.1093/bioinformatics/btu388

Fig. 1.

Fig. 1.

Link probability suppression in the presence of an identical regulator. For each target, the conditional link probabilities of SCO4230 (°) and SCO0000 (×) (conditioned on the other regulator being off) are plotted against their posterior link probabilities for the network inferred on the dataset D2×phoP comprising 121 genes, including the regulator SCO4230 and its artificial copy SCO0000. The conditional link probability is computed from the MCMC samples (18 000 samples) by conditioning on the respective duplicate being off. The theoretical relationship, Equation (3) with ρ=0.026 (posterior mean), is shown (dashed line). The conditional link probability of SCO4230 on D2×phoP is also plotted against the link probability of SCO4230 inferred on D1×phoP (+), the corresponding dataset that lacks the artificial regulator SCO0000