Table 1.
Medium + Poly I:C | Th2 pre-treatment + Poly I:C | |
---|---|---|
Cxcl1 | 2.3 ± 0.3 | 2.1 ± 0.4 |
Cxcl9 | 99.0 ± 27.7 | 178.9 ± 52.7+ |
Cxcl10 | 46.2 ± 29.8 | 210.5 ± 61.0* |
Cxcl11 | 8.6 ± 2.2 | 61.2 ± 10.8** |
Ccl5 | 18.7 ± 2.0 | 26.8 ± 10.3 |
Il6 | 1.0 ± 0.4 | 2.1 ± 0.2+ |
Il33 | 2.3 ± 0.3 | 1.2 ± 0.2* |
Tslp | 0.5 ± 0.2 | 0.9 ± 0.4 |
Ddx58 | 1.2 ± 0.4 | 1.9 ± 0.7 |
Ddx60 | 3.5 ± 0.8 | 5.4 ± 1.2 |
Ifih1 | 2.8 ± 0.7 | 3.5 ± 1.7 |
Oasl1 | 10.4 ± 3.1 | 9.6 ± 3.8 |
Stat1 | 3.2 ± 1.9 | 139.8 ± 30.0** |
Stat2 | 1.2 ± 0.5 | 1.9 ± 0.8 |
Ifit1 | 4.3 ± 0.8 | 20.4 ± 7.2* |
Ifitm3 | 1.0 ± 0.5 | 5.6 ± 1.3* |
MLE-12 cells stimulated with poly I:C for 4 hours following culture for 48 hours in either medium alone or medium containing IL-4 and IL-13. mRNA expression shown as stimulation ratio (mean ± s.e.m.) relative to cells cultured in medium alone. + 0.05 < p < 0.1; *p < 0.05; **p < 0.01 by ratio paired t-test, n = 5 separate experiments.