TABLE 1.
Subject Characteristics and Hormone Therapy Status
| Variable | All Women N = 485 n (%)a |
Hormone Therapyb
|
p | Type of Hormone Therapy
|
p | ||
|---|---|---|---|---|---|---|---|
| Yes N = 230 n (%)a |
No N = 254 n (%)a |
Estrogen Only N = 99 n (%)a |
Combined Estrogen + Progesterone N = 85 n (%)a |
||||
| Median survival time, mo | 50.0 | 80.0 | 37.5 | <0.001 | 83.0 | 87.0 | 0.83 |
| Age, mean ± SD | 60.1 ± 9.0 | 61.8 ± 7.6 | 58.6 ± 9.8 | <0.001 | 62.3 ± 7.2 | 59.6 ± 7.4 | 0.01 |
| Race | <0.001 | 0.33 | |||||
| White | 373 (76.9) | 198 (86.0) | 174 (68.5) | 81 (81.8) | 74 (87.1) | ||
| African American | 112 (23.1) | 32 (13.9) | 80 (31.5) | 18 (18.2) | 11 (12.9) | ||
| Smoking statusc | 0.03 | 0.06 | |||||
| Never | 37 (7.6) | 17 (7.4) | 20 (7.9) | 12 (12.1) | 3 (3.5) | ||
| Ex-smoker | 155 (32.0) | 87 (37.8) | 68 (26.9) | 42 (42.4) | 33 (38.8) | ||
| Current | 292 (60.3) | 126 (54.8) | 165 (65.2) | 45 (45.5) | 49 (57.7) | ||
| Histology | 0.13 | 0.23 | |||||
| Squamous cell | 42 (8.7) | 19 (8.3) | 23 (9.1) | 4 (4.0) | 10 (11.8) | ||
| Adenocarcinoma | 353 (72.8) | 178 (77.4) | 174 (68.5) | 80 (80.8) | 61 (71.8) | ||
| Large cell | 13 (2.7) | 5 (2.2) | 8 (3.2) | 3 (3.0) | 2 (2.4) | ||
| NSCLC, NOS | 77 (15.9) | 28 (12.2) | 49 (19.29) | 12 (12.1) | 12 (14.1) | ||
| Pack-years of smokingd, mean ± SD | 47.5 ± 29.5 | 49.3 ± 28.3 | 45.8 ± 30.5 | 0.22 | 49.2 ± 27.8 | 47.1 ± 27.9 | 0.62 |
| Stage at diagnosise | 0.01 | 0.47 | |||||
| Local | 162 (33.6) | 88 (38.4) | 74 (29.4) | 42 (42.4) | 30 (35.3) | ||
| Regional | 161 (33.4) | 81 (35.4) | 79 (31.4) | 37 (37.4) | 32 (37.7) | ||
| Distant | 159 (33.0) | 60 (26.2) | 99 (39.3) | 20 (20.2) | 23 (27.1) | ||
| Hormone therapy duration, mof | 0.78 | ||||||
| 1–41 | 73 (33.3) | N/A | N/A | 31 (31.6) | 21 (26.9) | ||
| 42–131 | 72 (32.8) | 34 (34.7) | 28 (35.9) | ||||
| 132 | 74 (33.8) | 33 (33.7) | 29 (37.2) | ||||
| Age at menopause, mean ± SD | 44.2 ± 8.1 | 43.6 ± 8.1 | 44.7 ± 8.2 | 0.15 | 41.4 ± 7.6 | 46.0 ± 7.9 | <0.001 |
| Education levelg | <0.001 | 0.62 | |||||
| <High school | 20 (4.1) | 3 (1.3) | 17 (6.7) | 1 (1.0) | 1 (1.2) | ||
| High school | 266 (55.0) | 116 (50.7) | 149 (58.7) | 52 (52.5) | 38 (45.2) | ||
| >High school | 198 (40.9) | 110 (48.0) | 88 (34.7) | 46 (46.5) | 45 (53.6) | ||
| Treatment with surgeryh | <0.001 | 0.06 | |||||
| No | 195 (40.3) | 74 (32.3) | 120 (47.2) | 25 (25.3) | 32 (38.1) | ||
| Yes | 289 (59.7) | 155 (67.7) | 134 (52.8) | 74 (74.8) | 52 (61.9) | ||
| Treatment with radiationi | 0.15 | 0.23 | |||||
| No | 278 (58.2) | 140 (61.7) | 138 (55.2) | 61 (62.9) | 46 (54.1) | ||
| Yes | 200 (41.8) | 87 (38.3) | 112 (44.8) | 36 (37.1) | 39 (45.9) | ||
| Vital status | <0.01 | 0.58 | |||||
| Alive | 175 (36.1) | 106 (46.1) | 69 (27.2) | 46 (46.5) | 43 (50.6) | ||
| Dead | 310 (63.9) | 124 (53.9) | 185 (72.8) | 53 (53.5) | 42 (49.4) | ||
a
Percentages may not add to 100.0 because of rounding.
b
Hormone use was missing for one case.
c
Smoking status was missing for one case.
d
Pack-years were missing for two cases.
e
Stage was missing for three cases.
f
Duration of use was missing for 11 cases.
g
Education level was missing for one case.
h
Surgery information was missing for one case.
i
Radiation information was missing for seven cases.
NSCLC, non–small-cell lung cancer; NOS, not otherwise specified; N/A, not applicable.