Table 1.

Rule-based filters for drugs and pesticides

Rule	Lipinski	Tice		Hao
Class	Drugs	Herbicides	Insecticides	Pesticides
MW	≤ 500	150 – 500	150 – 500	≤ 435
MLogP(*CLogP)	≤ 5	≤ 3.5	0 - 5	≤ 6*
HBD	≤ 5	≤ 3	≤ 2	≤ 2
HBA	≤ 10	2 - 12	1 – 8	≤ 6
RB	-	< 12	< 12	≤ 9
aromatic bonds	-	-	-	≤ 17

*MLogP [15] values were computed for Lipiniski's [3] and Tice's [11] rules and CLogP [16] values for Hao's [14] according to the original publications.