Figure 3.
GHB- and baclofen-elicited astrocytic [Ca2+]i transients are unaffected by block of glutamate receptors. Fluorescence traces show responses of astrocytes in a VTA slice to 10 mM GHB in control conditions and in the presence of APV. The summary bar graph on the right quantifies the lack of effect of NMDA, non-NMDA and mGluR antagonists (APV, NBQX and MTEP+ CPCCOEt, respectively) on the number of astrocytes responding to application of 10 mM GHB or 10 µM baclofen. (Online version in colour.)