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. 2014 Sep 24;5:185. doi: 10.3389/fneur.2014.00185

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Copyright © 2014 Hadders-Algra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cross-section through the cortex of a fetus of 24 PMA. The following layers can be distinguished, from the inside (bottom) to the outer surface (top): vz, the ventricular zone, which produces neurons; svz, the subventricular zone, which possibly is phylogenetically younger than the ventricular zone, and which produces neurons and glial cells (14); iz, the intermediate zone, i.e., the future white matter; sp, the subplate, which at this stage is very thick and harbors the transient fetal circuitry; cp, the cortical plate; mz, the marginal zone. Ingrowing afferents come from the basal forebrain (bf), thalamus (th), and monoaminergic brain stem nuclei (tegm ma). Figure by curtsy of Dr. Ivica Kostovic, University of Zagreb.