Figure 3.

Schematic representations of the reorganization of motor and sensory function after a unilateral lesion of the brain at early age. (A) Reorganization after a “preterm” unilateral lesion. The lesion involves the periventricular white matter. The reorganization includes (a) the persistence of ipsilateral corticospinal projections to the paretic hand originating in the contralesional hemisphere and (b) axonal plasticity of the thalamocortical afferents bypassing the lesion in the ipsi-lesional hemisphere. (B) Reorganization after a “term” unilateral lesion, which usually does not include the periventricular white matter. Motor and sensory functions of the paretic hand are organized in the lesioned hemisphere.