Table S1.
Check point analysis for particle size model adequacy evaluation
| A | B | C | D | Actual value, nm (± SD) | Predicted value, nm | Bias, % |
|---|---|---|---|---|---|---|
| 0 | 0 | −1 | −1 | 405.6±7.23 | 329.88 | 18.66 |
| 0 | 0 | −1 | 1 | 372.1±5.66 | 319.53 | 14.12 |
| 0 | 0 | 1 | −1 | 397.9±5.09 | 342.77 | 13.85 |
| 0 | 0 | 1 | 1 | 403.6±13.58 | 355.32 | 11.96 |
Notes: −1 denotes low variable level, 0 denotes the central point between the low and high variable levels, and 1 denotes high variable level. A, chitosan concentration; B, alginate concentration; C, repaglinide concentration; D, drug placement.
Abbreviation: SD, standard deviation.