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IC50 values of DTX formulation in the H40-PLA NPs alone or in combination with 30 μM CQ on MCF-7 cells following 24, 48 and 72 h treatment, respectively (n=6).
| Incubation time (h) | IC50 (μg/mL) | ||
|---|---|---|---|
| H40-PLANPs | H40-PLA NPs+CQ | ||
| 24 | 32.29 ± 1.41 | 4.55 ± 0.78 | |
| 48 | 11.39 ± 2.03 | 0.18 ± 0.07 | |
| 72 | 2.61 ± 0.73 | 0.03 ± 0.062 | |
