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Cytotoxic effects of FA-DOX/siRNA-L in KB, HeLa and Hep3B cells. Cells were treated with liposomes with the final siRNA concentration of 100 nM and DOX concentration of 1 mg/mL. The Hep3B cells were used as a negative control. The multiple groups were compared by one-way ANOVA with Dunnett's t-test. Data are expressed as mean ± SD (n = 3). *: P < 0.05; **: P < 0.01.
