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Opioids can break the commensalism of 2-member pathogen communities. Kaplan-Meier survival curves of C. elegans fed on ICU6-2 (A), ICU11-2 (B), ICU11-4 (C), and ICU4-4 (D) 2-member communities in the presence of an opioid (50 µM U-50,488) (n = 10/plate, 3 plates/group; P < 0.01). Data represent the cumulative results of 2 experiments. Exposure to opioids broke the commensalism in the ICU6-2 and ICU11-2 communities.
