Table 4.
Heterogenity test and Hardy-Weinberg Equilibrium (HWE) MDR1 gene polymorphism C3435T depending on the epilepsy classification.
| Genotyp | Epilepsy classification (n=82) | |||||||
|---|---|---|---|---|---|---|---|---|
| ILAE | Appleton | Siddiqui | Berg | |||||
| Good responsive | Resistant | Good responsive | Resistant | Good responsive | Resistant | Good responsive | Resistant | |
| CC | 2 (4.7%) | 8 (20.5%) | 5 (10.9%) | 5 (13.9%) | 5 (10.0%) | 5 (15.6%) | 7 (13.0%) | 3 (10.7%) |
| CT | 28 (65.1%) | 21 (53.8%) | 26 (56.5%) | 23 (63.9%) | 29 (58.0%) | 20 (62.5%) | 31 (57.4%) | 18 (64.3%) |
| TT | 13 (30.2%) | 10 (25.6%) | 15 (32.6%) | 8 (22.2%) | 16 (32.0%) | 7 (21.9%) | 16 (29.6%) | 7 (25.0%) |
| Hardy Weinberg test | p=0.15 | p=0.94 | p=0.66 | p=0.47 | p=0.54 | p=0.59 | p=0.64 | p=0.49 |
| Comparison of all genotypes* | 4.81 NS (p=0.09) |
1.11 NS (p=0.57) |
1.29 NS (p=0.53) |
0.36 NS (p=0.83) |
||||
| CC vs. the total of other genotypes | 3.44 NS (p=0.07) |
0.01 NS (p=0.74) |
0.17 NS (p=0.50) |
0.03 NS (p=0.99) |
||||
| CT vs. the total of other genotypes | 1.08 NS (p=0.30) |
0.46 NS (p=0.49) |
0.16 NS (p=0.68) |
0.036 NS (p=0.54) |
||||
| TT vs. the total of other genotypes | 0.21 NS (p=0.64) |
1.07 NS (p=0.33) |
0.99 NS (p=0.32) |
0.65 NS (p=0.20) |
||||
NS – not significant; p≥0.05;
*
χ2 test; p – value.