Fig. 5.

The evaluation of the contribution of cholesterol biosynthetic pathway. Four wells of TGEMs were incubated in DMEM containing 10% LPDS with compound(s) indicated below the graph for 24 h, and the apoptotic cells were detected by TUNEL method. Data are expressed as the mean ± SEM. *P < 0.05 and **P < 0.01, as determined by ANOVA followed by the Tukey-Kramer post hoc test. NS, nonsignificant difference.