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Effect of alirocumab, atorvastatin, and their combination on plaque morphology. Representative images of HPS-stained atherosclerotic lesions in a cross-section of the aortic root area for the control (A), 3 mg/kg alirocumab (B), 10 mg/kg alirocumab (C), atorvastatin (D), 3 mg/kg alirocumab + atorvastatin (E), and 10 mg/kg alirocumab + atorvastatin (F) groups, respectively, after 18 weeks of treatment.
